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Harlequin Fetus
Old 04-20-2005, 04:41 PM   #1
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Harlequin type ichthyosis, the most severe form of congenital ichthyosis, is characterized by a thickening of the keratin layer in fetal skin. The afflicted child is born not with skin, but massive, diamond-shaped scales. As well, the eyes, ears, mouth, and other appendages can be abnormally contracted. The scaly armor limits the child's movement, and because it is cracked where normal skin would fold, it is useless for skin's primary function -- protection. Bacteria and other contaminants easily pass into the cracks and can cause lethal infections.

The term comes from both the baby's facial expression and the diamond-shaped pattern of the scales (resembling the costume of a arlecchino), which are caused by severe hyperkeratosis. Seventeenth century entertainers known as jesters, or harlequins, wore costumes with diamond patterns on them, as well as a particular style of face paint. The features of the harlequin fetus resemble this stylized makeup, and their faces are often pulled tight into grim parodies of a clown's smile.
http://asylumeclectica.com/malady/ar.../harlequin.htm

http://www.ispub.com/ostia/index.php.../harlequin.xml

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